
Smilax spp.
Also known as Tu fu ling, Jamaica, Honduras or Spanish Sarsaparilla, (1) Mexican Sarsaparilla, (2) Honduras Sarsaparilla, (3) Jamaica Sarsaparilla, (See next page.).
Sarsaparilla once held a high reputation as an alterative; it is now considered practically valueless. Almost the only use made of it at present is as a vehicle for iodides and other alteratives. For this purpose the compound syrup is largely preferred. Sarsaparilla is not wholly inert and its long-continued use may cause ulceration of the mucosa of the intestines. Some believe it also to possess an active cardiosedative principle, probably sarsaponin.

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| Preparation | As written | Metric |
|---|---|---|
| Tincture (1:2-1:3) | 3-5 ml TID | 3-5 mL |
| Decoction | 2-3 tsp/c TID | |
| Dose, two to four fluid ounces three times a day | 59.15-118 mL | |
| Dose, ten to twenty grains, dissolved in water, three times a day | 648-1296 mg | |
| Fluid Extract of Sarsaparilla | Dose, from one-half to one dram. | 1944-3888 mg |
| Dose, 30 grains. | 1944-1944 mg |
Doses are reproduced from the sources for practitioners and are not a recommendation for any person.
Action and Therapy. Sarsaparilla once held a high reputation as an alterative; it is now considered practically valueless. Almost the only use made of it at present is as a vehicle for iodides and other alteratives. For this purpose the compound syrup is largely preferred. Sarsaparilla is not wholly inert and its long-continued use may cause ulceration of the mucosa of the intestines. Some believe it also to possess an active cardiosedative principle, probably sarsaponin.
Therapy. This agent is an active eliminant, possessing diuretic and alterative properties to a marked degree. It has long been a popular remedy for the treatment of blood dyscrasias, but is nearly always given in combination with other well known specific alteratives. In combination with potassium iodide, stillingia, corydalis, phytolacca, podophyllum, or other alteratives, it has been given in scrofula and secondary syphilis , and especially in cutaneous diseases depending upon blood dyscrasia, and in rheumatic and gouty conditions, with inactive kidneys irritated from the presence of large quantities of uric acid and the urates. It is not at present in general use.
Properties and Uses. The root of the sarsaparilla is placed among the most efficient alteratives, of the relaxant and moderately tonic grade. Its powers have been much overrated; and though good, it is more valuable for its pleasantness and mildness than for its potency.
Action, Medical Uses, and Dosage. Indian sarsaparilla has been successfully employed in venereal diseases, especially in cases where the South American sarsaparilla has proved inefficient. Dr. Ashburner says that it increases the appetite, acts as a diuretic, and improves the general health; "plumpness, clearness, and strength, succeeding to emaciation, muddiness, and debility." Likewise said to be useful in affections of the kidneys, scrofula, cutaneous diseases, and thrush.
Drawn from Cook's Physio-Medical Dispensatory; King's American Dispensatory, 18th edition (Felter and Lloyd); Ellingwood's American Materia Medica, Therapeutics and Pharmacognosy; Felter's Eclectic Materia Medica, Pharmacology and Therapeutics, and the Bountiful Herbs editorial.
Sarsaparilla stands in 10 documented formulas in the library, among them Compound Fluid Extract of Sarsaparilla.

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