Andrographis (Andrographis paniculata)
Andrographis paniculata
Western, Chinese and Ayurvedic herbalism
Western, Chinese and Ayurvedic herbalism

Andrographis

Andrographis paniculata

Also known as king of bitters, green chiretta, creat, kalmegh, Kalmegha, Bhunimba, Kirata (shared with Swertia).

CoolingDryingTaste: Bitter

Andrographis paniculata is an erect annual herb of the Acanthaceae that grows wild and is cultivated across the Indian plains, from Uttar Pradesh and Bengal to Tamil Nadu and Kerala, and through Sri Lanka and Southeast Asia. Its intensely bitter aerial parts are the Kalmegh of north India and the Nilavembu of the Tamil Siddha tradition, a cooling bitter for fevers, liver disorders and infections. In Ayurveda it stands as one of the plants called Bhunimba, the earth-neem, sharing that name with the Himalayan Swertia chirata.

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Bitter tonicAntipyreticImmunomodulatorAnti-inflammatoryHepatoprotectiveCholagogueAntimicrobialAntiviral (supportive)AnthelminticAntidiarrhealHypoglycemic (mild)ImmunostimulantAntiviralAntioxidantCholereticTonicStomachicAnticancerHypotensiveHypoglycaemicDigestive stimulantAntiplateletAntithrombotic

Indications what the tradition reached for it in

Specific indications

The first day of a cold or flu with a hot, raw throat, aching and a fever that is climbing, in a robust patient

A patient with a heavy, hot liver picture: nausea, bitter taste, right upper quadrant fullness and yellowish sclerae after illness or alcohol

Recurrent low fevers with loss of appetite in a warm, damp climate, where infection keeps returning

Acute watery diarrhea with fever and a hot abdomen in an otherwise strong patient

Safety

Pregnancy: Not for use in pregnancy

Breastfeeding: No data in nursing mothers; the tradition withholds strongly bitter, drying herbs during lactation, so avoid or use briefly under supervision.

The record lists 8 contraindications; open the plate in the library to read them in full.

In practice

Kalmegh belongs to the hot, robust, febrile patient, not the depleted or cold one. Ayurveda gives it as a fresh-leaf juice or a decoction at the onset of fever, especially fevers with a heavy liver and a bitter, coated mouth, and it is a standard component of the fever decoctions of the south.

In Ayurveda

Rasa: tikta (bitter). Virya: sheeta (cooling). Vipaka: katu (pungent). Guna: laghu (light), ruksha (dry). Dosha: pacifies pitta and kapha; aggravates vata in excess. Karma: jvaraghna (relieves fever); krimighna (anthelmintic); pittasaraka (drains excess pitta through the bowel); yakrit uttejaka (stimulates the liver); deepana (kindles digestion); pachana (digests ama); raktashodhana (purifies the blood); kushthaghna (relieves skin disease); shothahara (reduces swelling); vishaghna (counters poison). Classical indications: jvara (fever, including recurrent and malarial types); vishama jvara (intermittent fever); kamala (jaundice); yakrit vikara (liver disorders); krimi (worms); kushtha (skin disease); atisara and pravahika (diarrhea and dysentery); agnimandya (weak digestion); pratishyaya (rhinitis, common cold); shotha (swelling); prameha (urinary disorders). The whole plant, gathered in flower, is used dried as churna, as kwatha, as swarasa of the fresh leaf, and in fermented and tableted compounds; the Siddha tradition of Tamil Nadu makes Nilavembu kudineer, a fever decoction in which it is the lead herb. Classical formulations: Kalmegha churna, Kalmegha kwatha, Kalmegha navayasa lauha, Nilavembu kudineer, Kalmeghasava, Kalmegha ghana vati. Described in: Bhavaprakasha Nighantu, Raja Nighantu, Ayurvedic Pharmacopoeia of India.

Dosing as the sources wrote it

PreparationAs writtenMetric
Churna1-3 g powdered whole plant twice daily with honey or warm water1000-3000 mg
Kwatha40-80 mL decoction twice daily40-80 mL
Swarasa5-10 mL fresh leaf juice twice daily5-10 mL
Standardized extract200-400 mg extract three times daily, providing 60-200 mg andrographolides daily, for 5-10 days200-400 mg
Dried aerial partsDried aerial parts 3-6 g/day3000-6000 mg
DecoctionDecoction 20-25 g whole plant/day20000-25000 mg

Doses are reproduced from the sources for practitioners and are not a recommendation for any person.

From the sources

Overview. Andrographis paniculata is an erect annual herb of the Acanthaceae that grows wild and is cultivated across the Indian plains, from Uttar Pradesh and Bengal to Tamil Nadu and Kerala, and through Sri Lanka and Southeast Asia. Its intensely bitter aerial parts are the Kalmegh of north India and the Nilavembu of the Tamil Siddha tradition, a cooling bitter for fevers, liver disorders and infections. In Ayurveda it stands as one of the plants called Bhunimba, the earth-neem, sharing that name with the Himalayan Swertia chirata.

Clinical Notes. King of Bitters in Ayurveda/TCM clears heat, detoxifies, rids fever/toxins aerial parts primary standardize to andrographolide Kan Jang (Andrographis + eleuthero) studied for URTI promising adjunct for viral respiratory infections per RCTs/meta-analyses

Clinical Notes. Kalmegh belongs to the hot, robust, febrile patient, not the depleted or cold one. Ayurveda gives it as a fresh-leaf juice or a decoction at the onset of fever, especially fevers with a heavy liver and a bitter, coated mouth, and it is a standard component of the fever decoctions of the south.

action_hepatoprotective. Andrographolide ameliorates carbon tetrachloride-induced hepatotoxicity and protects against carbon tetrachloride-induced oxidative damage in rats; the herb was traditionally employed for sluggish liver and disorders of the liver.

In formulas

Andrographis stands in 6 documented formulas in the library, among them Mṛdvīkāriṣṭa, Tiktaka Ghṛta, Paṭolādi Ghṛta, Mahā Paṅcagavya Ghṛtā, Candraprabhā Vaṭī, Mehamudgara Rasa.

Often paired with

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