Corydalis

action-analgesic-sedative-cns. THP as well as DHCB has been shown to exhibit a wide number of pharmacological actions on the central nervous system, including analgesic and sedative effects; dl-THP exhibits a tranquilizing action in mice, and scientists have suggested that dl-THP blocks certain receptor sites (e.g., dopamine) in the brain to cause sedation and relieve pain.

action-anti-inflammatory. An extract from Corydalis has shown strong anti-inflammatory activity, inhibiting increased vascular permeability in mice, reducing acute paw edema in rats, suppressing adjuvant-induced edema in arthritic rats, and inhibiting histamine release from peritoneal mast cells in both acute and chronic phases of inflammation.

efficacy-pain-cold-pressor. In a controlled clinical trial using the cold-pressor test, a single oral administration of extracts of Corydalis yanhusuo and Angelicae dahuricae significantly decreased pain intensity scores (both P < .01) with a dose-related analgesic effect, suggesting potential clinical value for treating mild to moderate pain.

traditional-use-pain. In traditional Chinese medicine, corydalis is said to invigorate the blood, move qi, and alleviate all types of pain, including menstrual, abdominal, hernial and pain associated with cancer; it is used extensively by practitioners of Chinese herbal medicine for pain, especially abdominal pain.