
Citrus aurantium
Also known as Seville Orange, Zhi Shi (unripe), Zhi Ke (ripe), Sour Orange, Orange peel, Neroli, Orange Blossom, Petitgrain, zhǐ ké, zhǐ shí.
Bitter orange peel is the dried rind of the unripe or nearly ripe fruit of the sour orange tree, a small evergreen citrus long cultivated across the Mediterranean and now grown widely in warm climates worldwide. In Eclectic and European herbal medicine the peel has been valued as a classic aromatic bitter, used to rouse a weak appetite and settle a sluggish stomach, and it remains a common flavoring agent used to make other bitter medicines more palatable. It is distinct from the concentrated fruit extracts marketed for weight loss, which are standardized to much higher synephrine content and carry different safety concerns.

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| Preparation | As written | Metric |
|---|---|---|
| Immature fruit (Zhi Shi) decoction | Immature fruit (Zhi Shi) decoction: 3-9 g/day for stronger qi-breaking | 3000-9000 mg |
| Mature fruit/peel (Zhi Ke) decoction | Mature fruit/peel (Zhi Ke) decoction: 3-9 g/day for gentler qi-moving | 3000-9000 mg |
| Tincture (1:5) | Tincture (1:5): 2-4 ml three times daily | 2-4 mL |
| Powder/capsule | Powder/capsule: 1-3 g | 1000-3000 mg |
| Topical (diluted in carrier) | Topical: typical 1-3% in carrier; face/sensitive 0.5-1; dermal maximum 5%. Distilled flower oil ... NOT phototoxic (unlike expressed citrus peel). | |
| Internal (oral) | Not recommended internally ... insufficient current safety data for the essential oil; use the culinary herb or tea instead. No established oral oil dose. |
Doses are reproduced from the sources for practitioners and are not a recommendation for any person.
Overview. Bitter orange peel is the dried rind of the unripe or nearly ripe fruit of the sour orange tree, a small evergreen citrus long cultivated across the Mediterranean and now grown widely in warm climates worldwide. In Eclectic and European herbal medicine the peel has been valued as a classic aromatic bitter, used to rouse a weak appetite and settle a sluggish stomach, and it remains a common flavoring agent used to make other bitter medicines more palatable. It is distinct from the concentrated fruit extracts marketed for weight loss, which are standardized to much higher synephrine content and carry different safety concerns.
Clinical Notes. Bitter orange peel is reached for when digestion has simply slowed down: the patient picks at food, feels full quickly, and complains of gas and a heavy stomach after meals, often during recovery from illness or in older patients with a tired digestive tract.
Therapy. Stimulant, carminative and tonic, but used chiefly as a flavoring agent. This preparation is contained in both Compound Tincture of Cinchona and Compound Tincture of Gentian.
Properties and Uses. This article is a mild and grateful aromatic stimulant and relaxant, of moderate tonic properties. It warms the stomach, improves the appetite, and aids the expulsion of wind. It is rarely used alone; but is employed almost exclusively as an adjunct to the very bitter tonics and strong cathartics, to relieve their unpleasant taste and counterbalance their too local action.
Drawn from Cook's Physio-Medical Dispensatory; Felter's Eclectic Materia Medica, Pharmacology and Therapeutics, and the Bountiful Herbs editorial.
Bitter Orange stands in 120 documented formulas in the library, among them Tinctura Cinchonae Composita , Compound Tincture of Cinchona, Tinctura Gentianae Composita, Compound Tincture of Gentian, Classic Bitter Digestive Tonic, xuǎn dú fà bião tāng, jing jiè lián giáo tàng, rén shên bài dú sǎn.

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