Gymnema (Gymnema sylvestre)
Gymnema sylvestre
Western and Ayurvedic herbalism
Western and Ayurvedic herbalism

Gymnema

Gymnema sylvestre

Also known as gurmar, sugar destroyer, Australian cowplant, periploca of the woods, Small Indian Ipecac, Gurmar in Hindi “sugar destroyer”, Meshashringi, Madhunashini, Ajashringi.

WarmingDryingTaste: AstringentTaste: BitterTaste: Pungent

Gymnema sylvestre is a slow growing woody climber of the milkweed subfamily with opposite oval leaves and small yellow flowers, native to the deciduous forests of central and southern India and also found in Sri Lanka, tropical Africa and Australia. Ayurveda calls the leaf Meshashringi, ram's horn, from the shape of the fruit, and Madhunashini, destroyer of sweetness, because chewing it abolishes the taste of sugar for an hour or two. It is the classical herb for prameha and madhumeha, the urinary and metabolic disorders that include diabetes, and it is warming, drying and reducing in nature.

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HypoglycemicSweet taste suppressantInsulin secretagogue (preclinical)Inhibitor of intestinal glucose absorptionHypolipidemicBitter astringentAntiobesity (adjunct)Anti-inflammatoryAntimicrobialHepatoprotective (preclinical)Appetite suppressantInhibits glucose absorptionPancreatic beta cell trophorestorativeSweet taste suppressionantidiabetichypocholesterolemic

Indications what the tradition reached for it in

Specific indications

The heavy, sluggish kapha patient with rising blood sugar, a sweet tooth and afternoon drowsiness after meals

A newly diagnosed type 2 diabetic who wants to try diet and herbs before or alongside metformin

The dieter who knows what to do but cannot stop reaching for sugar, where chewing the leaf or taking the powder before meals flattens the craving

Elevated triglycerides and fasting glucose together in a patient with central weight gain

Safety

Pregnancy: Limited safety data in pregnancy

Breastfeeding: Lactation category=no data

The record lists 6 contraindications; open the plate in the library to read them in full.

In practice

The Ayurvedic physician gives Meshashringi for kapha-type prameha: the overweight, sedentary patient with sweet urine, lethargy, excess mucus and a strong appetite for sweets. The leaf powder is taken with warm water before the two main meals, or fresh leaves are chewed in the morning to spoil the taste of sweet foods for the rest of the day.

In Ayurveda

Rasa: kashaya (astringent), tikta (bitter), katu (pungent). Virya: ushna (heating). Vipaka: katu (pungent). Guna: laghu (light), ruksha (dry). Dosha: pacifies kapha and vata; may aggravate pitta in excess. Prabhava: madhunashana (abolishes the taste of sweetness and counters diabetes). Karma: pramehaghna (counters urinary and metabolic disorders); medohara (reduces fat); kaphahara (reduces kapha); deepana (kindles digestion); vishaghna (counters poison); krimighna (anthelmintic); hridya (supports the heart); kasahara (relieves cough); shothahara (reduces swelling); chakshushya (benefits the eyes). Classical indications: prameha (urinary disorders including diabetes); madhumeha (diabetes mellitus); medoroga (obesity); kasa (cough); shvasa (dyspnea); visha (snake and insect poisoning); krimi (worms); hridroga (heart disease); netraroga (eye disease); vrana (wounds). The leaf is the drug, chewed fresh to blunt the sweet taste, dried and powdered as churna with warm water before meals, decocted as kwatha, and used in compound antidiabetic powders. The root is used regionally for snakebite and as a paste on wounds. Classical formulations: Meshashringi churna, Ayaskriti, Meshashringyadi kwatha, Madhumehari churna (compound antidiabetic powders), Nishamalaki with Meshashringi (regional). Described in: Sushruta Samhita, Ashtanga Hridaya, Bhavaprakasha Nighantu, Dhanvantari Nighantu, Raja Nighantu, Ayurvedic Pharmacopoeia of India.

Dosing as the sources wrote it

PreparationAs writtenMetric
Churna3-6 g powdered leaf daily in divided doses before meals with warm water3000-6000 mg
Kwatha50-100 mL decoction twice daily50-100 mL
Standardized extract200-400 mg leaf extract standardized to gymnemic acids twice daily before meals200-400 mg
Kalka, topical5-10 g root or leaf paste applied to wounds or swellings5000-10000 mg
Tincture (1:2-1:3)1-3 ml TID1-3 mL
Powdered leaves400 mg-10 g/d (most research done on 400 mg/day)400-400 mg

Doses are reproduced from the sources for practitioners and are not a recommendation for any person.

From the sources

Overview. Gymnema sylvestre is a slow growing woody climber of the milkweed subfamily with opposite oval leaves and small yellow flowers, native to the deciduous forests of central and southern India and also found in Sri Lanka, tropical Africa and Australia. Ayurveda calls the leaf Meshashringi, ram's horn, from the shape of the fruit, and Madhunashini, destroyer of sweetness, because chewing it abolishes the taste of sugar for an hour or two. It is the classical herb for prameha and madhumeha, the urinary and metabolic disorders that include diabetes, and it is warming, drying and reducing in nature.

Clinical Notes. The Ayurvedic physician gives Meshashringi for kapha-type prameha: the overweight, sedentary patient with sweet urine, lethargy, excess mucus and a strong appetite for sweets. The leaf powder is taken with warm water before the two main meals, or fresh leaves are chewed in the morning to spoil the taste of sweet foods for the rest of the day.

primary-actions. Gymnema acts primarily as: Appetite suppressant, Hypoglycemic. Secondary actions include Inhibits glucose absorption, Hypolipidemic, Pancreatic beta cell trophorestorative.

indications. Gymnema is traditionally indicated for: Diabetes (type II), Diabetes (type I, caution), Sugar cravings, Hypercholesterolemia, Hypertriglyceridemia, Hyperlipidemia, Hyperglycemia, High cholesterol.

In formulas

Gymnema stands in 5 documented formulas in the library, among them Ayaskṛti, Paṅcatikta Ghṛta, Mahā Kalyāṇaka Ghṛta, Mahā Viṣagarbha Taila, Blood Sugar Support Formula.

Often paired with

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