
Inonotus obliquus
Also known as Birch Mushroom.
Primarily used in Russian/Siberian traditional medicine Grows as sclerotium on birch trees Dual extraction (water for polysaccharides, alcohol for triterpenoids) optimal Preclinical evidence strong, limited human clinical trials Sustainability concerns due to slow growth

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| Preparation | As written | Metric |
|---|---|---|
| Decoction/tea: 1-3g sclerotium powder simmered 15-20 min in 1 cup water, 1-2x daily | 1000-3000 mg | |
| Tincture: 2-4 mL, 2-3x daily | 2-4 mL | |
| Powder/capsules: 1-3g daily | 1000-3000 mg |
Doses are reproduced from the sources for practitioners and are not a recommendation for any person.
Clinical Notes. Primarily used in Russian/Siberian traditional medicine Grows as sclerotium on birch trees Dual extraction (water for polysaccharides, alcohol for triterpenoids) optimal Preclinical evidence strong, limited human clinical trials Sustainability concerns due to slow growth
antioxidant-action. Chaga is a redox/antioxidant and antimutagenic agent that inhibits free-radical oxidation; seven small phenolic antioxidant components (including protocatechuic acid, caffeic acid and syringic acid) isolated from the fruiting body show significant scavenging activity against ABTS and DPPH radicals.
constituents. Chaga's principal bioactive constituents are a full spectrum of immune-enhancing polysaccharides (endo-polysaccharide/beta-glucans), lanostane-type triterpenoids (inotodiol, trametenolic acid, lanosterol, inonotsuoxides A and B), betulin and betulinic acid, and small phenolic antioxidants.
immune-enhancement. Chaga water-soluble endo-polysaccharide enhances immune response, inducing production of interferons, stimulating B-cell proliferation and polyclonal IgM antibody production, and increasing expression of IL-1beta, IL-6, TNF-alpha and iNOS in macrophages, acting as an immune response modifier.
Chaga stands in 5 documented formulas in the library, among them Amṛtaprāśa Ghṛta, Chāgalādya Ghṛta, Bṛhatmāṣa Taila, Prabhākara Rasa, Sūcikābharaṇa Rasa.

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