
Cordyceps sinensis
Also known as Dong chong xia cao, Chong cao, Yartsa gunbu.
Most commonly available as cultured cordyceps (CS-4) Decreases LDL oxidation and platelet aggregation Increases coronary and cerebral circulation Regulates arrythmias Modulates endocrine system function Increases testosterone when hormone levels are low, but does not alter androgen levels when they are normal Inhibits age-related mental decline Increases NK cells, T helper cells, IL1, TNF-alpha, interferon-gamma Protective to kidneys against effects of toxins such as cyclosporine Decreases hematuria and proteinuria in patients w/ chronic nephritis Inhibited systemic lupus erythematosus in animals Decreases complications when used after renal transplants Enhances oxygen utilization Prevents beta-amyloid cell...

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| Preparation | As written | Metric |
|---|---|---|
| CS-4 extract (4:1) | 3-6 g/d for therapeutic actions or 1-3 g/d for maintenance | 3000-6000 mg |
| Powdered | 1-10 g/d | 1000-10000 mg |
Doses are reproduced from the sources for practitioners and are not a recommendation for any person.
Clinical Notes. Most commonly available as cultured cordyceps (CS-4) Decreases LDL oxidation and platelet aggregation Increases coronary and cerebral circulation Regulates arrythmias Modulates endocrine system function Increases testosterone when hormone levels are low, but does not alter androgen levels when they are normal Inhibits age-related mental decline Increases NK cells, T helper cells, IL1, TNF-alpha, interferon-gamma Protective to kidneys against effects of toxins such as cyclosporine Decreases hematuria and proteinuria in patients w/ chronic nephritis Inhibited systemic lupus erythematosus in animals Decreases complications when used after renal transplants Enhances oxygen utilization Prevents beta-amyloid cell...
primary-action. The fungus is a broad immunomodulator that activates macrophages and enhances natural killer cell and T-lymphocyte function, with one clinical study reporting NK cell cytotoxicity rising by nearly 39 percent versus placebo.
action. The fungus modulates endocrine function and can raise testosterone when hormone levels are low without pushing androgens above normal, in line with its traditional use for kidney-yang deficiency, impotence and lower-back weakness.
indication. Systematic reviews and meta-analyses support the fungus as an adjunct in chronic kidney disease and renal dysfunction, with observed improvements in serum creatinine, creatinine clearance and proteinuria, and better outcomes when used alongside immunosuppression in kidney transplant recipients.

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