
Trametes versicolor
Also known as yún zhī.
Approved in Japan as PSK for adjunct cancer therapy (gastric colorectal) Supports immune recovery post-chemo/radiotherapy Biological response modifier Use high-quality beta-glucan sources Phase 1 trial

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| Preparation | As written | Metric |
|---|---|---|
| Dried powder/capsules | Dried powder/capsules 3-9 g/day | 3000-9000 mg |
| Decoction | Decoction 9-27 g/day | 9000-27000 mg |
| PSK/PSP extracts | PSK/PSP extracts 3 g/day | 3000-3000 mg |
| Tincture | Tincture (traditional) Phase 1 trial |
Doses are reproduced from the sources for practitioners and are not a recommendation for any person.
Clinical Notes. Approved in Japan as PSK for adjunct cancer therapy (gastric colorectal) Supports immune recovery post-chemo/radiotherapy Biological response modifier Use high-quality beta-glucan sources Phase 1 trial
action. Coriolus versicolor (Trametes versicolor), also known as Turkey Tail, is a well-researched immune enhancing agent in Integrative Oncology and a mushroom of wide use in Japan as an adjunct to biomedical cancer treatments; aqueous extracts display a wide array of biological activities, including stimulatory effects on different immune cells and inhibition of cancer growth.
indication. In patients with Dukes B or Dukes C colorectal cancer treated with UFT plus PSK for 24 months after curative surgery and monitored up to 10 years, the 10-year survival was significantly better for patients treated with PSK, with a hazard ratio of 0.3.
indication. A meta-analysis provided strong evidence that Yun Zhi (Coriolus versicolor) would have survival benefit; in patients with breast cancer, gastric cancer, or colorectal cancer treated with chemotherapy, the effect of the combination on the overall 5-year survival rate was more evident, but not in esophageal or nasopharyngeal carcinoma.

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