Thunder god vine

Tripterygium wilfordii

Also known as Lei gong teng.

CoolingTaste: BitterTaste: Pungent

Use only standardized root extracts Improper preparation (e.g. leaves, unskinned root) highly toxic and potentially fatal Monitor LFTs, renal function, CBC Reversible infertility Traditional TCM use for heat/toxicity clearing

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Anti-inflammatoryImmunomodulatorAntifibrotic

Indications what the tradition reached for it in

Joint pain
Nephritic syndrome
IgA nephropathy
Ulcerative colitis
Systemic lupus erythematosus
Nephrotic syndrome
Gout
Joint swelling
Crohn's disease
Ankylosing spondylitis
Psoriasis
Rheumatoid arthritis
Fever
Inflammation
Inflammatory bowel disease
Multiple sclerosis
Autoimmune disease
Lupus nephritis
Immunodeficiency
Pain
Recurrent infections
Arthritis
Skin conditions
Infection

Safety

Low dose botanical. Used in drop doses in the classical practice; not a plant to dose freely.

Pregnancy: Pregnancy Caution

Breastfeeding: Lactation (source flag notSafeInLactation)

The record lists 3 contraindications; open the plate in the library to read them in full.

Dosing as the sources wrote it

Preparation	As written	Metric
Standardized extract/tablets	Standardized extract/tablets 180-570 mg/day (RA, up to 20 weeks)	180-570 mg
Refined extract	Refined extract 20-120 mg/day	20-120 mg
Topical tincture	Topical tincture 5-6x/day (RA

Doses are reproduced from the sources for practitioners and are not a recommendation for any person.

From the sources

Clinical Notes. Use only standardized root extracts Improper preparation (e.g. leaves, unskinned root) highly toxic and potentially fatal Monitor LFTs, renal function, CBC Reversible infertility Traditional TCM use for heat/toxicity clearing

indications. Thunder god vine is traditionally indicated for: Joint pain, Nephritic syndrome, IgA nephropathy, Ulcerative colitis, Systemic lupus erythematosus, Nephrotic syndrome, Gout, Joint swelling, Crohn's disease, Ankylosing spondylitis, Psoriasis, Rheumatoid arthritis, Fever, Inflammation, Inflammatory bowel disease, and 9 further conditions.

dose-reference. Reference preparation/dosing for Thunder god vine: Standardized extract/tablets 180-570 mg/day (RA, up to 20 weeks); Refined extract 20-120 mg/day; Decoction (traditional TCM); Topical tincture 5-6x/day (RA

safety-cautions. Thunder god vine - Contraindications: Additive immunosuppression with drugs, Osteoporosis, Weakened immune system | Side effects: Gastrointestinal upset, Diarrhea, Nausea, Vomiting, Headache, Dizziness, Skin rash/redness, Leukopenia | Safety flags: not considered safe in pregnancy; not considered safe during lactation; low-dose / narrow therapeutic window (use caution).

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