Pacific Yew (Taxus brevifolia)
Taxus brevifolia
Western Herbalism
Western Herbalism

Pacific Yew

Taxus brevifolia

Also known as Western Yew.

CoolingTaste: Bitter

Pacific Yew acts primarily as: Antineoplastic (paclitaxel - microtubule stabilizer), Cytotoxic, Antiproliferative, Antiangiogenic. Secondary actions include Antineoplastic, Cytotoxic, TOXIC - not for lay internal use.

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Actions

Antineoplastic (paclitaxel - microtubule stabilizer)CytotoxicAntiproliferativeAntiangiogenicAntineoplasticTOXIC - not for lay internal use

Indications what the tradition reached for it in

Safety

Recognised toxicity. This plant carries a toxicity flag in the record; it is for trained practitioners only.

Low dose botanical. Used in drop doses in the classical practice; not a plant to dose freely.

Breastfeeding: Lactation (source flag notSafeInLactation)

The record lists 7 contraindications; open the plate in the library to read them in full.

Dosing as the sources wrote it

PreparationAs writtenMetric
Semisynthesis from 10-deacetylbaccatin III in the renewable needles of Taxus baccata now spares wild bark

Doses are reproduced from the sources for practitioners and are not a recommendation for any person.

From the sources

primary-actions. Pacific Yew acts primarily as: Antineoplastic (paclitaxel - microtubule stabilizer), Cytotoxic, Antiproliferative, Antiangiogenic. Secondary actions include Antineoplastic, Cytotoxic, TOXIC - not for lay internal use.

indications. Pacific Yew is traditionally indicated for: Botanical source of paclitaxel (Taxol), Pharmaceutical use in ovarian, breast and non-small-cell lung cancer chemotherapy, Researched whole-plant and Taxus chinensis aqueous extracts in integrative oncology, Native American topical and ceremonial uses, NOT a self-administered internal botanical.

constituents. Notable constituents of Pacific Yew include: Taxane diterpenes: paclitaxel (taxol), ~0.01-0.04% of dried inner bark, Taxine alkaloids (taxine A and B), Cephalomannine, 10-deacetylbaccatin III, Baccatin III, Lignans (taxiresinol), Taxine B is the principal cardiotoxin.

dose-reference. Reference preparation/dosing for Pacific Yew: Not used as a home tincture or internal botanical; Paclitaxel is a standardized intravenous chemotherapeutic dosed by oncology; Semisynthesis from 10-deacetylbaccatin III in the renewable needles of Taxus baccata now spares wild bark; Any historical decoction/topical use carries serious risk and is not recommended; Listed for pharmacognostic completeness

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