
Cascara Amarga
Also known as Cascara amarga, Bitter bark, Cascarilla amarga.
Cascara Amarga, botanically Picramnia antidesma, is a small tree or shrub of the family Picramniaceae native to Central America, the Caribbean, and parts of northern South America. The bark, sometimes traded as Honduras bark, was used by nineteenth century eclectic physicians as a bitter alterative distinct from the unrelated Rhamnus purshiana (Cascara Sagrada), which is a laxative bark from a different plant family entirely. In the eclectic materia medica it held a niche place as a gentle tonic and blood purifier for chronic skin disease, particularly where syphilis was suspected as an underlying cause.

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Ask HerbertChronic pustular eruption of syphilitic origin appearing in a run-down, debilitated patient
Weak, easily irritated stomach with poor appetite in a patient needing a mild bitter before deeper alterative treatment is tolerated
Pregnancy: Avoid in pregnancy: there is no modern safety data and historical use does not substitute for evidence of safety.
Breastfeeding: Avoid in lactation: no safety data exists for this plant in nursing mothers.
The record lists 4 contraindications; open the plate in the library to read them in full.
Eclectic writers reached for Cascara Amarga in cases of chronic, pustular skin disease occurring against a background of general debility, most often where a syphilitic history was present or suspected.
| Preparation | As written | Metric |
|---|---|---|
| Fluid extract (historical, 1:1) | 0.5-2 mL three times daily | 0.5-2 mL |
| Tincture (1:5) | 2-4 mL three times daily | 2-4 mL |
Doses are reproduced from the sources for practitioners and are not a recommendation for any person.
Overview. Cascara Amarga, botanically Picramnia antidesma, is a small tree or shrub of the family Picramniaceae native to Central America, the Caribbean, and parts of northern South America. The bark, sometimes traded as Honduras bark, was used by nineteenth century eclectic physicians as a bitter alterative distinct from the unrelated Rhamnus purshiana (Cascara Sagrada), which is a laxative bark from a different plant family entirely. In the eclectic materia medica it held a niche place as a gentle tonic and blood purifier for chronic skin disease, particularly where syphilis was suspected as an underlying cause.
Clinical Notes. Eclectic writers reached for Cascara Amarga in cases of chronic, pustular skin disease occurring against a background of general debility, most often where a syphilitic history was present or suspected.
Cascara Amarga, sometimes known as Honduras Bark, is advised in syphilis as an active alterative. The line of its action is where there is chronic skin affection or where the pustular variety of the syphiloderm prevails, the conditions being induced by debility, thus needing a specific tonic influence. It soothes the stomach, overcomes sensitiveness or ready irritability of this organ, increases the appetite, and improves general tonicity.
Drawn from Ellingwood's American Materia Medica, Therapeutics and Pharmacognosy, and the Bountiful Herbs editorial.

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