
Citrus x paradisi
Also known as Pink Grapefruit, Pomelo Hybrid.
Grapefruit acts primarily as: Digestive bitter, Antioxidant, Antimicrobial (seed extract), Lipid-modulating, Appetite-regulating, CYP3A4 and P-glycoprotein inhibitor (furanocoumarins), Uplifting (oil). Secondary actions include Stimulate digestion and bile, Cool and clear, Support metabolism, Uplift mood (oil).

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| Preparation | As written | Metric |
|---|---|---|
| Tincture (1:5) of peel | Tincture (1:5) of peel: 2-4 ml | 2-4 mL |
| Topical (diluted in carrier) | Topical: typical 1-4% in carrier; face/sensitive 0.5-1; dermal maximum 4%. Mildly phototoxic ... the highest safe limit among common expressed citrus. | |
| Internal (oral) | Not recommended internally ... insufficient current safety data for the essential oil; use the culinary herb or tea instead. No established oral oil dose; note grapefruit-drug interaction concerns with the fruit. |
Doses are reproduced from the sources for practitioners and are not a recommendation for any person.
primary-actions. Grapefruit acts primarily as: Digestive bitter, Antioxidant, Antimicrobial (seed extract), Lipid-modulating, Appetite-regulating, CYP3A4 and P-glycoprotein inhibitor (furanocoumarins), Uplifting (oil). Secondary actions include Stimulate digestion and bile, Cool and clear, Support metabolism, Uplift mood (oil).
indications. Grapefruit is traditionally indicated for: Sluggish digestion and low appetite, Metabolic support and weight management (adjunct), Antioxidant and cardiovascular wellness, Candida and microbial overgrowth (grapefruit seed extract, traditional), Low mood and grogginess (aromatherapy), Oily skin (topical oil).
constituents. Notable constituents of Grapefruit include: Furanocoumarins (bergamottin, 6',7'-dihydroxybergamottin), Flavonoids (naringin, naringenin), Volatile oil (limonene), Vitamin C, Pectin, Lycopene (pink/red).
dose-reference. Reference preparation/dosing for Grapefruit: Fruit and fresh juice as food (note drug interactions); Tincture (1:5) of peel: 2-4 ml; Grapefruit seed extract: per product (antimicrobial use); Essential oil for aromatherapy or diluted topical (phototoxic); Always reconcile against the patient's medication list

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