Chinese Herbalism
Xi Shu
Camptotheca acuminata
Also known as Happy Tree, Cancer Tree, Tree of Joy.
Xi Shu acts primarily as: Antineoplastic (camptothecin - topoisomerase I inhibitor), Cytotoxic, Antiviral, Anti-inflammatory. Secondary actions include Clear heat and toxin, Antineoplastic, Cytotoxic, TOXIC - not for lay internal use.
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Indications what the tradition reached for it in
- Botanical source of camptothecin (parent of the chemotherapy drugs topotecan and irinotecan)
- Pharmaceutical/oncology use in colorectal, ovarian and small-cell lung cancer (as semisynthetic derivatives)
- Traditional Chinese use for cancers and stubborn conditions
- NOT appropriate for casual internal self-dosing
Safety
Low dose botanical. Used in drop doses in the classical practice; not a plant to dose freely.
Breastfeeding: Lactation (source flag notSafeInLactation)
The record lists 7 contraindications; open the plate in the library to read them in full.
From the sources
primary-actions. Xi Shu acts primarily as: Antineoplastic (camptothecin - topoisomerase I inhibitor), Cytotoxic, Antiviral, Anti-inflammatory. Secondary actions include Clear heat and toxin, Antineoplastic, Cytotoxic, TOXIC - not for lay internal use.
indications. Xi Shu is traditionally indicated for: Botanical source of camptothecin (parent of the chemotherapy drugs topotecan and irinotecan), Pharmaceutical/oncology use in colorectal, ovarian and small-cell lung cancer (as semisynthetic derivatives), Traditional Chinese use for cancers and stubborn conditions, NOT appropriate for casual internal self-dosing.
constituents. Notable constituents of Xi Shu include: Quinoline alkaloid camptothecin and analogues (10-hydroxycamptothecin), Other monoterpene indole alkaloids, Flavonoids, Tannins.
dose-reference. Reference preparation/dosing for Xi Shu: Not used as a home tincture or internal botanical; The clinically useful agents are the semisynthetic, water-soluble derivatives topotecan and irinotecan, dosed by oncology; Crude decoctions historically used in Chinese oncology carry serious toxicity and are not recommended; Listed for pharmacognostic completeness
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